Association of cyclinD1 copy number changes with histological type in ovarian tumors
نویسندگان
چکیده
منابع مشابه
DNA copy number changes in malignant ovarian germ cell tumors.
Malignant ovarian germ cell tumors (OGCTs) include immature teratomas (ITs), dysgerminomas (DGs), endodermal sinus tumors (ESTs), choriocarcinomas, and embryonal carcinomas. Knowledge about the genetic changes associated with malignant OGCT development is sparse. We therefore analyzed 25 OGCTs (12 DGs, 4 ESTs, and 9 ITs) for gains and losses by comparative genomic hybridization. In total, more ...
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چکیده ندارد.
Allele-specific copy number analysis of tumors.
We present an allele-specific copy number analysis of the in vivo breast cancer genome. We describe a unique bioinformatics approach, ASCAT (allele-specific copy number analysis of tumors), to accurately dissect the allele-specific copy number of solid tumors, simultaneously estimating and adjusting for both tumor ploidy and nonaberrant cell admixture. This allows calculation of "ASCAT profiles...
متن کاملHuman Cancer Biology Copy Number Aberrations in Benign Serous Ovarian Tumors: A Case for Reclassification?
Purpose: Serous ovarian carcinomas are the predominant epithelial ovarian cancer subtype and it has been widely believed that some or all of these may arise from precursors derived from the ovarian surface epithelium or fimbriae, although direct molecular evidence for this is limited. This study aimed to conduct copy number (CN) analysis using a series of benign and borderline serous ovarian tu...
متن کاملCopy number aberrations in benign serous ovarian tumors: a case for reclassification?
PURPOSE Serous ovarian carcinomas are the predominant epithelial ovarian cancer subtype and it has been widely believed that some or all of these may arise from precursors derived from the ovarian surface epithelium or fimbriae, although direct molecular evidence for this is limited. This study aimed to conduct copy number (CN) analysis using a series of benign and borderline serous ovarian tum...
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ژورنال
عنوان ژورنال: Acta Oncologica
سال: 2004
ISSN: 0284-186X,1651-226X
DOI: 10.1080/02841860410018548